11β-HSD1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES4290
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3290
Human swiss prot no
P28845
Immunogen
Synthesized peptide derived from 11β-HSD1 . at AA range: internal
Isotype
IgG
Observed band
35kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011],
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More Info
More Info
11β-HSD1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
