14-3-3 ε rabbit pAb

14-3-3 ε rabbit pAb

Item number: ES1541
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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14-3-3 ε rabbit pAb

14-3-3 ε rabbit pAb

$148.00

14-3-3 ε rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human 14-3-3 epsilon. AA range:206-255
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
29kD
Geneid human
7531
Human swiss prot no
P62258
Cellular localization
Nucleus . Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008],

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