14-3-3σ (Phospho Ser186) rabbit pAb

Name: 14-3-3σ (Phospho Ser186) rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES20196

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB; ELISA

Cellular localization

Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway.

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

2810

Human swiss prot no

P31947

Immunogen

Synthesized peptide derived from human 14-3-3σ (Phospho Ser186)

Isotype

IgG

Observed band

30kD

Product weight

0.005kg

Reactivity

Human;Mouse

Recommended dilutions

WB 1:1000-2000 ELISA 1:5000-20000

Source

Rabbit

Storage

-20°C/1 year

Background

function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.,function:p53-regulated inhibitor of G2/M progression.,similarity:Belongs to the 14-3-3 family.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,

14-3-3σ (Phospho Ser186) rabbit pAb

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