1A68 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES18548
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Golgi membrane,endoplasmic reticulum,Golgi apparatus,Golgi medial cisterna,plasma membrane,integral component of plasma membrane,cell surface,ER to Golgi transport vesicle membrane,membrane,integral component of membrane,
Clonality
Polyclonal
Concentration
1 mg/ml
Human swiss prot no
P01891
Immunogen
Synthesized peptide derived from human 1A68 AA range: 1-51
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1：500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney trans
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Product Citations
Product Citations
More Info
More Info
1A68 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
