2',3'-cGAMP
Regular price
$1,265.00 USD
Sale price
Regular price
Unit price
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Shipping calculated at checkout.
Available in stock (500)
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Bioactivity
2'3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2'3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2'3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm.
Casnumber
1441190-66-4
Formula
C20H24N10O13P2
Mw
674.41
Psmiles
C1C2C(C(C(O2)N3C=NC4=C3N=C(NC4=O)N)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C(N=CN=C76)N)O)OP(=O)(O1)O)O)OC1C2C(C(C(O2)N3C=NC4=C3N=C(NC4=O)N)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C(N=CN=C76)N)O)OP(=O)(O1)O)O)OC1C2C(C(C(O2)N3C=NC4=C3N=C(NC4=O)N)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C(N=CN=C76)N)O)OP(=O)(O1)O)O)OC1C2C(C(C(O2)N3C=NC4=C3N=C(NC4=O)N)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C(N=CN=C76)N)O)OP(=O)(O1)O)O)O
Purity
>99%
Shelf life
12 months
Shipping conditions
blue ice
Solubility
Water 4 mg/mL (May need ultrasonic and warming)
Storage
Freeze (< -15 °C); Minimize light exposure;
Target synonyms
2'-3'-cyclic GMP-AMP;2',3'-cGAMP
Background
Background
2',3'-cGAMP or cGAMP (Cyclic guanosine monophosphate"adenosine monophosphate) is produced in mammalian cells by cGAS (cGAMP synthase) from ATP and GTP upon cyto
Product Citations
Product Citations
More Info
More Info
2',3'-cGAMP
Regular price
$1,265.00 USD
Sale price
Regular price
Unit price
/per

