2',7'-dichlorodihydrofluorescein

Vendor: Abmole

Type: Biochemical Assay

SKU: M59028

$126.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent reactive oxygen species (ROS) probe with an excitation wavelength of 485-500 nm and an emission wavelength of 515-530 nm. 2,7-Dichlorodihydrofluorescein is first hydrolyzed by intracellular esterases and then oxidized by ROS to generate non-biomembrane-permeable, highly fluorescent 2,7-dichlorofluorescein (DCF). 2,7-Dichlorodihydrofluorescein can undergo oxidation reactions with a variety of ROS (such as ·OH, H2O2, ONOO-, etc.) and is used to quantitatively detect the level of oxidative stress inside and outside cells. The fluorescence intensity of DCF is positively correlated with the ROS concentration.
Casnumber
106070-31-9
Formula
C20H12Cl2O5
Mw
403.21
Purity
≥99.0%
Solubility
DMSO ≥ 100 mg/mL
Target synonyms
DCFH2
2',7'-dichlorodihydrofluorescein

2',7'-dichlorodihydrofluorescein

$126.50 USD