2-Methoxyestradiol

Vendor: Abmole

Type: Molecular

SKU: M1992

$74.75 USD
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Coa

Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
2-methoxyestradiol (2-ME2), an endogenous metabolite of 17β -estradiol (E2) with oral activity, is an apoptosis inducer and angiogenesis inhibitor with effective antitumor activity. Methoxyestradiol can also destabilize microtubules. Methoxyestradiol is a potent inhibitor of superoxide dismutase (SOD) and reactive oxygen species (ROS) that can induce autophagy in transformed cell line HEK293, cancer cell line U87 and HeLa.
Casnumber
362-07-2
Formula
C19H26O3
Mw
302.41
Psmiles
COC1=C(O)C=C2CCC3C(CCC4(C)C(O)CCC34)C2=C1
Purity
>99.0%
Solubility
DMSO ≥ 100 mg/mL
Target synonyms
2ME2; NSC-659853
2-Methoxyestradiol

2-Methoxyestradiol

$74.75 USD