3-Deazaadenosine hydrochloride

Vendor: Abmole

Type: Molecular

SKU: M11185

$189.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
3-deazaadenosine HCl (3-DZA, c3Ado) is an effective s-adenosylhomocysteine hydrolase inhibitor with Ki value of 3.9 μM. 3-deazaadenosine HCl inhibits the transcription of TNF-α and IL-1β induced by bacterial liposolysaccharide. 3-deazaadenosine HCl inhibits NF-κB transcriptional activity, prevents CARBOxyl methylation of Ras induced by FCS, and reduces ERK1/2 and Akt phosphorylation induced by FCS.
Casnumber
86583-19-9
Mw
302.72
Psmiles
Cl.NC1=NC=CC2=C1N=C[N]2C3OC(CO)C(O)C3O
Purity
>99.0%
Solubility
DMSO 40 mg/mL; Water ≥ 50 mg/mL
Target synonyms
3-DZA HCl, c3Ado HCl
3-Deazaadenosine hydrochloride

3-Deazaadenosine hydrochloride

$189.75 USD