3BP1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES10250
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cell projection . Cell junction, tight junction . Cell junction, adherens junction . Cell projection, phagocytic cup . Nucleus . Cytoplasm, cytosol . Localizes at the leading edge of migrating cells (PubMed:21658605, PubMed:24841563). Accumulation at forming phagocytic cups is PI3 kinase/PI3K-dependent and is specific for sites of large particles engagement and their phosphatidylinositol 3,4,5-triphosphate membrane content (PubMed:26465210). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
23616
Human swiss prot no
Q9Y3L3
Immunogen
Synthesized peptide derived from human protein . at AA range: 170-250
Isotype
IgG
Observed band
77kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
function:Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.,sequence caution:Translated as Cys.,similarity:Contains 1 BAR domain.,similarity:Contains 1 Rho-GAP domain.,
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More Info
More Info
3BP1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

