3HAO rabbit pAb
Vendor: ELK Biotechnology
SKU: ES9308
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cytoplasm, cytosol .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
23498
Human swiss prot no
P46952
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Isotype
IgG
Observed band
31kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq, Jul 2008],
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More Info
More Info
3HAO rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
