3pK rabbit pAb
Vendor: ELK Biotechnology
SKU: ES1547
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus . Cytoplasm . Predominantly located in the nucleus, when activated it translocates to the cytoplasm.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
7867
Human swiss prot no
Q16644
Immunogen
The antiserum was produced against synthesized peptide derived from human MAPK3. AA range:301-350
Isotype
IgG
Observed band
42kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and
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Documents
Documents
Product Citations
Product Citations
More Info
More Info
3pK rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
