3pK rabbit pAb

3pK rabbit pAb

Item number: ES1547
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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3pK rabbit pAb

3pK rabbit pAb

$148.00

3pK rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human MAPK3. AA range:301-350
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
42kD
Geneid human
7867
Human swiss prot no
Q16644
Cellular localization
Nucleus . Cytoplasm . Predominantly located in the nucleus, when activated it translocates to the cytoplasm.
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and

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