4E-BP1 (phospho Thr69) rabbit pAb

4E-BP1 (phospho Thr69) rabbit pAb

Item number: ES4385
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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4E-BP1 (phospho Thr69) rabbit pAb

4E-BP1 (phospho Thr69) rabbit pAb

$148.00

4E-BP1 (phospho Thr69) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from mouse 4E-BP1 around the phosphorylation site of Thr69. AA range:35-84
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
12kD
EIF4EBP1 encodes one member of a family of translation repressor proteins. The eukaryotic translation initiation factor 4E binding protein 1 directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

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