4E-BP1 (phospho Thr70) rabbit pAb

Name: 4E-BP1 (phospho Thr70) rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES5079

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

IHC;IF;ELISA

Cellular localization

nucleoplasm,cytoplasm,cytosol,protein complex,

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

1978

Human swiss prot no

Q13541

Immunogen

The antiserum was produced against synthesized peptide derived from human 4E-BP1 around the phosphorylation site of Thr70. AA range:36-85

Isotype

IgG

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

eukaryotic translation initiation factor 4E binding protein 1(EIF4EBP1) Homo sapiens This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],

4E-BP1 (phospho Thr70) rabbit pAb

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