53BP1 (phospho-Ser1778) rabbit pAb

53BP1 (phospho-Ser1778) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES18530

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB
Cellular localization
Nucleus . Chromosome . Chromosome, centromere, kinetochore . Localizes to the nucleus in absence of DNA damage (PubMed:28241136). Following DNA damage, recruited to sites of DNA damage, such as double stand breaks (DSBs): recognizes and binds histone H2A monoubiquitinated at 'Lys-15' (H2AK15Ub) and histone H4 dimethylated at 'Lys-20' (H4K20me2), two histone marks that are present at DSBs sites (PubMed:23333306, PubMed:23760478, PubMed:24703952, PubMed:28241136, PubMed:17190600). Associated with kinetochores during mitosis (By similarity). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
7158
Human swiss prot no
Q12888
Immunogen
Synthesized phosho peptide around human 53BP1 (Ser1778)
Isotype
IgG
Observed band
213kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:1000-2000
Source
Rabbit
Storage
-20°C/1 year
53BP1 (phospho-Ser1778) rabbit pAb

53BP1 (phospho-Ser1778) rabbit pAb

$148.00 USD