8-CPT-2Me-cAMP sodium

Vendor: Abmole

Type: Molecular

SKU: M30401

$517.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
8-CPT-2Me-cAMP sodium is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50> 10 μM). 8-CPT-2Me-cAMP sodium stimulates Epac-mediated Ca2+ release in pancreatic β-cells in vitro.
Casnumber
634207-53-7
Formula
C17H16ClN5NaO6PS
Mw
507.82
Psmiles
COC1C2C(COP(=O)(O2)O)OC1N3C4=NC=NC(=C4N=C3SC5=CC=C(C=C5)Cl)N
Purity
≥99.0%
Solubility
DMSO 125 mg/mL (ultrasonic and warming and heat to 60°C)
8-CPT-2Me-cAMP sodium

8-CPT-2Me-cAMP sodium

$517.50 USD