8ODP rabbit pAb
Vendor: ELK Biotechnology
SKU: ES9331
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$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
[Isoform p18]: Cytoplasm, cytosol . Mitochondrion matrix . Nucleus . Mostly present in cytosol (PubMed:7782328). A minor proportion is mitochondrial (PubMed:7782328). A very small amount of the protein is associated with nuclei (PubMed:7782328). .; [Isoform p26]: Mitochondrion matrix .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
4521
Human swiss prot no
P36639
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Isotype
IgG
Observed band
21kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer is
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More Info
More Info
8ODP rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
