A 196

Vendor: Abmole

Type: Molecular

SKU: M6362

$138.00 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
A-196 is a potent selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively, and biochemically inhibits SUV4-20 in a substrate-competitive manner. In addition, A-196 is a first-in-class chemical probe for SUV4-20, which can be used to study the role of histone methyltransferases in genome integrity.
Casnumber
1982372-88-2
Formula
C18H16Cl2N4
Mw
359.25
Psmiles
ClC1=C(Cl)C=C2C(=C1)C(=NN=C2C3=CC=NC=C3)NC4CCCC4
Purity
>99.0%
Solubility
DMSO 7.18 mg/mL
A 196

A 196

$138.00 USD