A-582941 dihydrochloride

Vendor: Abmole

Type: Molecular

SKU: M43973

$270.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
A-582941 dihydrochloride is a potent, selective, partial agonist of α7 nAChR across the blood-brain barrier, with Ki values of 10.8 nM in rat meninges and 16.7 nM in human frontal cortex.Additionally, A-582941 dihydrochloride binds to human 5- and 5HT3 receptors with a Ki value of 150 nM. In addition, A-582941 dihydrochloride can bind to human 5- HT3 receptors at a Ki value of 150 nM. A-582941 dihydrochloride can be used in studies of various neurodegenerative diseases and cognitive deficits.
Casnumber
848591-90-2
Formula
C17H22Cl2N4
Mw
353.29
Psmiles
CN1CC2CN(CC2C1)C3=NN=C(C=C3)C4=CC=CC=C4
Purity
>99.0%
Solubility
DMSO 100 mg/mL
A-582941 dihydrochloride

A-582941 dihydrochloride

$270.25 USD