A-769662

Vendor: Abmole

Type: Molecular

SKU: M3444

$96.60 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
A-769662 is a potent, reversible AMPK activator with EC50of 0.8 μM, little effect on GPPase/FBPase activity. A-769662 inhibits the function of the 26S proteasome by an AMPK-independent mechanism and leads to cell cycle arrest. A-769662 directly stimulates partially purified rat liver AMPK (EC50 = 0.8 μM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC50 = 3.2 μM).
Casnumber
844499-71-4
Formula
C20H12N2O3S
Mw
360.39
Psmiles
OC1=CC=CC=C1C2=CC=C(C=C2)C3=CSC4=C3C(=C(C#N)C(=O)N4)O
Purity
99.54%
Solubility
DMSO 35 mg/mL
A-769662

A-769662

$96.60 USD