a-actinin (4A12) Mouse mAb

a-actinin (4A12) Mouse mAb

Item number: EM1261
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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a-actinin (4A12) Mouse mAb

a-actinin (4A12) Mouse mAb

$148.00

a-actinin (4A12) Mouse mAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Applications
IHC
Source
Mouse
Recommended dilutions
IHC 1:100-200
Immunogen
Recombinant Protein
Isotype
IgG1
Clonality
Monoclonal
Concentration
1mg/mL
Observed band
103kDa
Geneid human
87
Human swiss prot no
P12814
Cellular localization
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane
α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.

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