A Cyclase VIII rabbit pAb
Vendor: ELK Biotechnology
SKU: ES4642
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF;ELISA
Cellular localization
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Apical cell membrane . Cell junction, synapse . Cell projection, dendrite . Cell projection, axon . Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse, postsynaptic density . Membrane raft . Membrane, coated pit . Cytoplasmic vesicle, clathrin-coated vesicle membrane . Membrane, caveola . Localized to dendritic arbors (By similarity). Monomeric N-glycosylated species localizes in membrane raft. In contrast, monomeric unglycosylated forms are enriched in clathrin-coated pits and vesicles. Dimers are also localized outside of membrane rafts. Membrane raft localization and integrity is indispensable for CCE-stimulated adenylate cyclase activity (By similarity). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
114
Human swiss prot no
P40145
Immunogen
The antiserum was produced against synthesized peptide derived from human ADCY8. AA range:591-640
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008],
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More Info
More Info
A Cyclase VIII rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

