ABCA4 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES10155
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Membrane ; Multi-pass membrane protein . Endoplasmic reticulum . Cytoplasmic vesicle . Cell projection, cilium, photoreceptor outer segment . Localized to the rim and incisures of rod outer segments disks. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
24
Human swiss prot no
P78363
Immunogen
Synthesized peptide derived from human protein . at AA range: 630-710
Isotype
IgG
Observed band
250kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are
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Product Citations
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More Info
More Info
ABCA4 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
