ABCAC rabbit pAb

ABCAC rabbit pAb

Item number: ES9418
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ABCAC rabbit pAb

ABCAC rabbit pAb

$148.00

ABCAC rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IHC;IF
Source
Rabbit
Recommended dilutions
IHC-p 1:50-300
Immunogen
Synthesized peptide derived from human protein . at AA range: 2170-2250
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
285kD
Geneid human
26154
Human swiss prot no
Q86UK0
Cellular localization
Cytoplasmic vesicle, secretory vesicle membrane ; Multi-pass membrane protein . Golgi apparatus membrane . Localizes in the limiting membrane of the lamellar granules (LGs) (PubMed:17927575). Trafficks from the Golgi apparatus to the lamellar granules (LGs) at the cell periphery in the uppermost granular layer keratinocytes where ABCA12-positive LGs fuse with the keratinocyte-cell membrane to secrete their lipid content to the extracellular space of the stratum corneum (PubMed:16007253, PubMed:17927575). Co-localizes through the Golgi apparatus to the cell periphery with glucosylceramide (PubMed:17927575). .
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],

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