ABCBB rabbit pAb

ABCBB rabbit pAb

Vendor: ELK Biotechnology

SKU: ES9453

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB;ELISA
Cellular localization
Apical cell membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Endosome . Cell membrane ; Multi-pass membrane protein . Internalized at the canalicular membrane through interaction with the adapter protein complex 2 (AP-2) (PubMed:22262466). At steady state, localizes in the canalicular membrane but is also present in recycling endosomes. ABCB11 constantly and rapidly exchanges between the two sites through tubulo-vesicles carriers that move along microtubules. Microtubule-dependent trafficking of ABCB11 is enhanced by taurocholate and cAMP and regulated by STK11 through a PKA-mediated pathway. Trafficking of newly synthesized ABCB11 through endosomal compartment to the bile canalicular membrane is accelerated by cAMP but not by taurocholat
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
8647
Human swiss prot no
O95342
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
145kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
ABCBB rabbit pAb

ABCBB rabbit pAb

$148.00 USD