ABCC8 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES9430
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6833
Human swiss prot no
Q09428
Immunogen
Synthesized peptide derived from human protein . at AA range: 500-580
Isotype
IgG
Observed band
173kD
Product weight
0.005kg
Reactivity
Human;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for
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More Info
More Info
ABCC8 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
