ABCG2 rabbit pAb
ABCG2 rabbit pAb

ABCG2 rabbit pAb

Item number: ES4288
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ABCG2 rabbit pAb

ABCG2 rabbit pAb

$148.00

ABCG2 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IF;WB;IHC;ELISA
Source
Rabbit
Recommended dilutions
IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ABCG2. AA range:461-510
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
75kD
Geneid human
9429
Human swiss prot no
Q9UNQ0
Cellular localization
Cell membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Mitochondrion membrane ; Multi-pass membrane protein . Enriched in membrane lipid rafts. .
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

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