ABCG2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES4288
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IF;WB;IHC;ELISA
Cellular localization
Cell membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Mitochondrion membrane ; Multi-pass membrane protein . Enriched in membrane lipid rafts. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
9429
Human swiss prot no
Q9UNQ0
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ABCG2. AA range:461-510
Isotype
IgG
Observed band
75kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
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Documents
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Product Citations
Product Citations
More Info
More Info
ABCG2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
