ACBI1

Vendor: Abmole

Type: Molecular

SKU: M13389

$506.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
ACBI1 is an effective and synergistic PROTAC inhibitor of SMARCA2, SMARCA4 and PBRM1, with DC50 of 6 nM, 11 nM and 32 nM in MV-4-11 cells, respectively. ACBI1 can induce antiproliferative effect and apoptosis.
Casnumber
2375564-55-7
Formula
C49H58FN9O7S
Mw
936.12
Psmiles
CC1=C(SC=N1)C2=CC(=C(CNC(=O)C3CC(O)CN3C(=O)C(NC(=O)C4(F)CC4)C(C)(C)C)C=C2)OCCOC5=CC=C(CN6CCN(CC6)C7=C(N)N=NC(=C7)C8=C(O)C=CC=C8)C=C5
Purity
>99.0%
Solubility
DMSO ≥ 60 mg/mL
ACBI1

ACBI1

$506.00 USD