Acetyl Kine rabbit pAb

Name: Acetyl Kine rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES20844

$148.00 USD

Shipping calculated at checkout.

Documents

Manuals

Supplier image

Available in stock (100)

Customs clearance fees may apply
Worldwide shipping available.

For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB

Clonality

Polyclonal

Immunogen

Recombinant Protein of Acetyl Kine

Isotype

IgG

Product weight

0.005kg

Reactivity

Species independent

Recommended dilutions

WB: 1:1000-2000

Source

Rabbit

Storage

-20°C/1 year

Background

Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) .Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis.Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport.The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases, and HDACs have become promising targets for anti-cancer drugs currently in development.

Acetyl Kine rabbit pAb

Documents

Product Overview

Background

Documents

Documents

Product Citations

More Info