Acetyl NF kB P65（K314/K315) (5G11) Mouse mAb
Vendor: ELK Biotechnology
SKU: EM1377
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC
Cellular localization
Cytoplasm, Nucleus
Clonality
Monoclonal
Concentration
1mg/mL
Geneid human
5970
Human swiss prot no
Q04206
Immunogen
Synthetic Peptide
Isotype
IgG1
Observed band
65kDa
Product weight
0.005kg
Reactivity
Human, Mouse, Rat
Recommended dilutions
IHC 1:100-200
Source
Mouse
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Background
Background
NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.
Documents
Documents
Documents
Product Citations
Product Citations
More Info
More Info
Acetyl NF kB P65（K314/K315) (5G11) Mouse mAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
