ACHA2 rabbit pAb

ACHA2 rabbit pAb

Item number: ES18494
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ACHA2 rabbit pAb

ACHA2 rabbit pAb

$148.00

ACHA2 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:500-2000
Immunogen
Synthesized peptide derived from human ACHA2 AA range: 219-269
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1135
Human swiss prot no
Q15822
Cellular localization
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009],

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