Actinonin

Vendor: Abmole

Type: Molecular

SKU: M28206

$92.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities.
Casnumber
13434-13-4
Formula
C19H35N3O5
Mw
385.5
Psmiles
CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1COCCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1COCCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1COCCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
Purity
≥99.0%
Solubility
DMSO 50 mg/mL (ultrasonic)
Target synonyms
(-)-Actinonin
Actinonin

Actinonin

$92.00 USD