ADAM10 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES1010
Regular price
$148.00 USD
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Regular price
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Available in stock (100)
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle . Cell projection, axon . Cell projection, dendrite . Cell junction, adherens junction . Cytoplasm . Is localized in the plasma membrane but is also expressed in the Golgi apparatus and in clathrin-coated vesicles derived likely from the Golgi (PubMed:12475894). During long term depression, it is recruited to the cell membrane by DLG1 (PubMed:23676497). The immature form is mainly located near cytoplasmic fibrillar structures, while the mature form is predominantly located at zonula adherens and the cell membrane (PubMed:30463011). The localization and clustering of mature ADAM10 to zonula adherens is regulated by AFDN, TSPAN33,
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
102
Human swiss prot no
O14672
Immunogen
Synthesized peptide derived from ADAM10 . at AA range: 170-250
Isotype
IgG
Observed band
85kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
ADAM metallopeptidase domain 10(ADAM10) Homo sapiens Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016],
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More Info
More Info
ADAM10 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

