Adaptaquin

Vendor: Abmole

Type: Molecular

SKU: M6406

$120.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Adaptaquin is a hIF-prolyl hydroxylase-2 (PHD2) inhibitor. Adaptaquin blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. Adaptaquin exhibits neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models, via inhibition of ATF4 dependent genes. Brain penetrant. Also antioxidant.
Casnumber
385786-48-1
Formula
C21H16ClN3O2
Mw
377.82
Psmiles
OC1=C(NC(C2=CC=C(Cl)C=C2)C3=C(O)C4=C(C=CC=N4)C=C3)N=CC=C1
Purity
>99.0%
Solubility
DMSO 37.78 mg/mL
Adaptaquin

Adaptaquin

$120.75 USD