Adezmapimod

Vendor: Abmole

Type: Molecular

SKU: M1781

$138.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Adezmapimod (SB203580) is a P38 MAPK inhibitor with an IC50 of 0.3-0.5 μM, which is 10 times less selective than SAPK3(106T) and SAPK4(106T), and inhibits PKB phosphorylation with an IC50 of 3-5 μM.
Casnumber
152121-47-6
Formula
C21H16FN3OS
Mw
377.43
Psmiles
C[S](=O)C1=CC=C(C=C1)C2=NC(=C([NH]2)C3=CC=NC=C3)C4=CC=C(F)C=C4
Purity
99.97%
Solubility
DMSO 20 mg/mL (ultrasonic and warming)
Target synonyms
SB203580; RWJ 64809; PB 203580
Adezmapimod

Adezmapimod

$138.00 USD