ADS032

Vendor: Abmole

Type: Molecular

SKU: M54576

$235.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
ADS032 is a dual inhibitor of NLRP1 and NLRP3 that rapidly, reversibly and stably inhibits inflammasome formation and reduces NLPR1 and NLRP3 activation of human-derived macrophages and bronchial epithelial cells to secrete and mature IL-1β and TNF-α, and reduces NLRP3-induced ASC speck formation. In addition, ADS032 protects mice from the deadly influenza A virus, reduces lung inflammation and improves survival.
Casnumber
2757333-37-0
Formula
C22H29NO4S
Mw
403.53
Psmiles
CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)CCCC(=O)O
Purity
>99.0%
Solubility
DMSO 100 mg/mL
ADS032

ADS032

$235.75 USD