AKAP 79 rabbit pAb

AKAP 79 rabbit pAb

Item number: ES1622
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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AKAP 79 rabbit pAb

AKAP 79 rabbit pAb

$148.00

AKAP 79 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human AKAP5. AA range:1-50
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
47kD
Geneid human
9495
Human swiss prot no
P24588
Cellular localization
Postsynaptic recycling endosome membrane ; Lipid-anchor . Associates with lipid rafts. .
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008],

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