AKAP9 rabbit pAb

AKAP9 rabbit pAb

Item number: ES9089
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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AKAP9 rabbit pAb

AKAP9 rabbit pAb

$148.00

AKAP9 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IHC;IF
Source
Rabbit
Recommended dilutions
IHC-p 1:50-300
Immunogen
Synthesized peptide derived from human protein . at AA range: 2610-2690
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
430kD
Geneid human
10142
Human swiss prot no
Q99996
Cellular localization
Golgi apparatus . Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasmic in parietal cells (PubMed:9915845). Recruited to the Golgi apparatus by GM130/GOLGA2 (PubMed:25657325). Localization at the centrosome versus Golgi apparatus may be cell line-dependent. In SKBr3 and HEK293F cells, exclusively located at the centrosome (PubMed:29162697). In HeLa, MDA-MB231 and RPE-1 cells, detected at the Golgi apparatus (PubMed:25217626, PubMed:29162697). In SK-BR-3 cells, recruited to the centrosome in the presence of CDK5RAP2 (PubMed:29162697). .
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008],

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