AKAP9 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES9089
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF
Cellular localization
Golgi apparatus . Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasmic in parietal cells (PubMed:9915845). Recruited to the Golgi apparatus by GM130/GOLGA2 (PubMed:25657325). Localization at the centrosome versus Golgi apparatus may be cell line-dependent. In SKBr3 and HEK293F cells, exclusively located at the centrosome (PubMed:29162697). In HeLa, MDA-MB231 and RPE-1 cells, detected at the Golgi apparatus (PubMed:25217626, PubMed:29162697). In SK-BR-3 cells, recruited to the centrosome in the presence of CDK5RAP2 (PubMed:29162697). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
10142
Human swiss prot no
Q99996
Immunogen
Synthesized peptide derived from human protein . at AA range: 2610-2690
Isotype
IgG
Observed band
430kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
IHC-p 1:50-300
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008],
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More Info
More Info
AKAP9 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

