ALDH2 rabbit pAb

ALDH2 rabbit pAb

Item number: ES4085
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ALDH2 rabbit pAb

ALDH2 rabbit pAb

$148.00

ALDH2 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human ALDH2. AA range:41-90
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
56kD
Geneid human
217
Human swiss prot no
P05091
Cellular localization
Mitochondrion matrix.
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform,

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