ALMS1 rabbit pAb

ALMS1 rabbit pAb

Item number: ES1642
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ALMS1 rabbit pAb

ALMS1 rabbit pAb

$148.00

ALMS1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from ALMS1 . at AA range: 1530-1610
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
460kD
Geneid human
7840
Human swiss prot no
Q8TCU4
Cellular localization
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Associated with centrosomes and basal bodies at the base of primary cilia. Specifically locates to the proximal ends of centrioles and basal bodies. Colocalizes partially with NCAPD2 at these sites. During mitosis localizes to both spindle poles.
This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. [provided by RefSeq, Apr 2014],

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