Alrizomadlin

Vendor: Abmole

Type: Molecular

SKU: M10781

$264.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Alrizomadlin (APG-115) is an oral active small molecule MDM2 protein inhibitor that binds to MDM2 protein.IC50 value and Ki The values are 3.8 nM and 1 nM, respectively. Alrizomadlin blocks MDM2 interaction with p53 and induces cell cycle arrest and apoptosis in a p53-dependent manner.
Casnumber
1818393-16-6
Formula
C34H38Cl2FN3O4
Mw
642.59
Psmiles
CCN1C(C(C2(C13CCCCC3)C4=C(C=C(C=C4)Cl)NC2=O)C5=C(C(=CC=C5)Cl)F)C(=O)NC67CCC(CC6)(CC7)C(=O)O
Purity
>98.5%, ee.: 100%
Solubility
DMSO 90 mg/mL
Target synonyms
APG-115; AA-115
Alrizomadlin

Alrizomadlin

$264.50 USD