AMD 3465

Vendor: Abmole

Type: Molecular

SKU: M59298

$299.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4. AMD 3465 inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells. AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50 = 1-10 nM). AMD 3465 inhibits CXCL-12-induced growth in U87 and Daoy cells.
Casnumber
185991-24-6
Formula
C24H38N6
Mw
410.6
Purity
≥99.0%
Solubility
Water ≥ 50 mg/mL
Target synonyms
GENZ-644494
AMD 3465

AMD 3465

$299.00 USD