AMG 232

Vendor: Abmole

Type: Molecular

SKU: M10374

$322.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AMG 232 is an extremely potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC50 = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED50 = 9.1 mg/kg). *The compound is unstable in solutions, freshly prepared is recommended
Casnumber
1352066-68-2
Formula
C28H35Cl2NO5S
Mw
568.55
Psmiles
CC(C)C(CS(=O)(=O)C(C)C)N1C(C(CC(C1=O)(C)CC(=O)O)C2=CC(=CC=C2)Cl)C3=CC=C(C=C3)Cl
Purity
>99%
Solubility
DMSO ≥ 48 mg/mL
Target synonyms
Navtemadlin ; KRT-232
AMG 232

AMG 232

$322.00 USD