AMG PERK 44

Vendor: Abmole

Type: Molecular

SKU: M28985

$258.75 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG PERK 44 induces autophagy.
Casnumber
1883548-84-2
Formula
C34H29ClN4O2
Mw
561.07
Psmiles
CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(C=C6)C.Cl
Purity
≥99.0%
Solubility
DMSO 25 mg/mL (ultrasonic)
AMG PERK 44

AMG PERK 44

$258.75 USD