AMGO2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11318
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Nucleus . Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons (By similarity). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
347902
Human swiss prot no
Q86SJ2
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Isotype
IgG
Observed band
57kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
function:Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.,similarity:Belongs to the immunoglobulin superfamily. AMIGO family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.,subunit:Binds itself as well as AMIGO1 and AMIGO3.,tissue specificity:Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.,
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Documents
Documents
Product Citations
Product Citations
More Info
More Info
AMGO2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
