Amitriptyline

Vendor: Abmole

Type: Molecular

SKU: M20793

$60.95 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Amitriptyline (MK-230, N-750, Ro41575) is an inhibitor of the serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki values of 3.45 nM and 13.3 nM, respectively, and also inhibits the histamine receptor H1, the histamine receptor H4, 5-HT2, and the Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. It can also inhibit histamine receptor H1, histamine receptor H4, 5-HT2 and Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively, and can be used in studies of depression and neuropathic pain.
Casnumber
50-48-6
Formula
C20H23N
Mw
277.4
Psmiles
CN(C)CC\C=C1/C2=C(CCC3=CC=CC=C13)C=CC=C2
Purity
>99%
Target synonyms
MK-230; N-750; Ro41575
Amitriptyline

Amitriptyline

$60.95 USD