Amphiphysin II rabbit pAb

Name: Amphiphysin II rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES4046

$148.00 USD

Shipping calculated at checkout.

Documents

Manuals

Supplier image

Available in stock (100)

Customs clearance fees may apply
Worldwide shipping available.

For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC;IF;ELISA

Cellular localization

[Isoform BIN1]: Nucleus . Cytoplasm . Endosome . Cell membrane, sarcolemma, T-tubule .; [Isoform IIA]: Cytoplasm .

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

274

Human swiss prot no

O00499

Immunogen

Synthesized peptide derived from the C-terminal region of human Amphiphysin II.

Isotype

IgG

Observed band

64kD

Product weight

0.005kg

Reactivity

Mouse;Rat

Recommended dilutions

Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016],

Amphiphysin II rabbit pAb

Documents

Product Overview

Background

Documents

Documents

Product Citations

More Info