AMPKα1/2 (phospho Thr183/172) rabbit pAb

Item number: ES1451
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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AMPKα1/2 (phospho Thr183/172) rabbit pAb

$148.00

AMPKα1/2 (phospho Thr183/172) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat;Monkey;Pig
Applications
IF;WB;IHC;ELISA
Source
Rabbit
Recommended dilutions
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
63kD
Geneid human
5562/5563
Human swiss prot no
Q13131/P54646
Cellular localization
Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

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