AMPKα2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES20835
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .
Clonality
Polyclonal
Geneid human
5563
Human swiss prot no
P54646
Immunogen
Recombinant Protein of AMPKα2
Isotype
IgG
Observed band
62kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB: 1:1000-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008],
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More Info
AMPKα2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
