AMPKβ2 Rabbit pAb

AMPKβ2 Rabbit pAb

Item number: ES20834
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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AMPKβ2 Rabbit pAb

AMPKβ2 Rabbit pAb

$148.00

AMPKβ2 Rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB
Source
Rabbit
Recommended dilutions
WB: 1:1000-2000
Immunogen
Recombinant Protein of AMPKβ2
Isotype
IgG
Clonality
Polyclonal
Observed band
30kD
Geneid human
5565
Human swiss prot no
O43741
Cellular localization
nucleoplasm,cytosol,nucleotide-activated protein kinase complex,
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],

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