AMPKβ2 Rabbit pAb
Vendor: ELK Biotechnology
SKU: ES20834
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
nucleoplasm,cytosol,nucleotide-activated protein kinase complex,
Clonality
Polyclonal
Geneid human
5565
Human swiss prot no
O43741
Immunogen
Recombinant Protein of AMPKβ2
Isotype
IgG
Observed band
30kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB: 1:1000-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],
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More Info
AMPKβ2 Rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
