AMPKγ1/2/3 rabbit pAb

Name: AMPKγ1/2/3 rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES6751

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IF;ELISA

Cellular localization

nucleoplasm,cytosol,membrane,nucleotide-activated protein kinase complex,extracellular exosome,

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

5571/51422/53632/

Human swiss prot no

P54619/Q9UGJ0/Q9UGI9

Immunogen

The antiserum was produced against synthesized peptide derived from human PRKAG1/2/3. AA range:46-95

Isotype

IgG

Observed band

38kD

Product weight

0.005kg

Reactivity

Human;Mouse;Rat

Recommended dilutions

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

AMPKγ1/2/3 rabbit pAb

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